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Menopause Hormone Therapy and Gallbladder Disease
Hormone Therapy Guide

Menopause Hormone Therapy and Gallbladder Disease

What's the Connection? Ask Dr. Jen

Dr. Jen Gunter's avatar
Dr. Jen Gunter
Apr 11, 2025
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Menopause Hormone Therapy and Gallbladder Disease
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“I’m wondering if there is any kind of evidence linking gallbladder problems to MHT?”

A great question!

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Short Take

Both estrogen and progestogens can be involved in gallbladder disease. Oral menopause hormone therapy (MHT) is linked with an increased risk of gallbladder disease based on the highest quality evidence (randomized, double-blind, placebo-

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