5 Comments

Looking forward to more posts about the menstrual cycle! I was very surprised to discover just the other day (aged 40!) that variations of up to 8 days in cycle length are considered "regular". I was on the pill for 15 years (so super-regular cycles - period predicted to within a 12h window) before having a baby, then switched to a copper IUD at 3 month pp. Since my period came back around 10 months pp, my cycles have varied from 20 to 29 days in length. Initially, this was merely mildly annoying but I was also diagnosed with ADHD last year and started taking methylphenidate, which it turns out works significantly less well for about 2-5 days before my period (an apparently really common but very under-researched phenomenon in women with ADHD). I can up my dose on those days but not knowing when "those days" will be means I need to have at least a couple of bad days before I know for sure it's happening. Hoping to go back on the pill when I see my OB next month to see if that helps.

I didn't find anything in the archives (apologies if I've missed it) so I would really appreciate it if you did a post (or part of a post) on the effects of the menstrual cycle on ADHD and ADHD medication.

Expand full comment

Is their data on menstrual changes with other infections and vaccinations? I’d be curious to know if the menstrual cycle always changes a bit when the immune system is tackling something significant.

Expand full comment

Sadly, no! That is what prompted a lot of outrage. However, what we have learned so far about the COVID-19 vaccine and menstruation is that the changes for almost everyone appear to be minimal, which is reassuring.

Expand full comment

It would have been interesting to look at when in the cycle the Covid symptoms or vaccination occurred (totally understand this would be difficult but it does sound like many subjects reported specific dates). Physiologically, I would expect that a major stressor in the late follicular phase might interfere with the LH surge and delay ovulation, while the same stressor in the luteal phase might have no effect.

Expand full comment

I am guessing they didn't have that level of data, or they do, and it's for another study. One hypothesis about the two doses per cycle phenomenon is that the first dose is given very early in the cycle.

Expand full comment